 James DentonSuperman / Clark Kent (voice) | Superman / Clark Kent (voice) |
 Christina HendricksLois Lane (voice) | Lois Lane (voice) |
 Anthony LaPagliaLex Luthor (voice) | Lex Luthor (voice) |
 Ed AsnerPerry White (voice) | Perry White (voice) |
 Linda CardelliniNasthalthia Luthor (voice) | Nasthalthia Luthor (voice) |
 Matthew Gray GublerJimmy Olsen (voice) | Jimmy Olsen (voice) |
 Arnold VoslooBar-El (voice) | Bar-El (voice) |
 Frances ConroyMartha Kent (voice) | Martha Kent (voice) |
 John DiMaggioSamson / Ultra-Sphinx (voice) | Samson / Ultra-Sphinx (voice) |
 Alexis DenisofDr. Leo Quintum (voice) | Dr. Leo Quintum (voice) |
 Chris CoxLead Agent (voice) | Lead Agent (voice) |
 Steve BlumAtlas / General Sam Lane / Astronaut #1 (voice) | Atlas / General Sam Lane / Astronaut #1 (voice) |
 Obba BabatundéJudge / Bibliobot (voice) | Judge / Bibliobot (voice) |
 Robin Atkin DownesSolaris (voice) | Solaris (voice) |
 Michael GoughParasite (voice) | Parasite (voice) |
 Finola HughesLilo (voice) | Lilo (voice) |
 Kevin Michael RichardsonSteve Lombard / Lizard Man / Convict (voice) | Steve Lombard / Lizard Man / Convict (voice) |
 Fred TatascioreKrull / Robots / Astronaut #2 (voice) | Krull / Robots / Astronaut #2 (voice) |
 Cathy CavadiniFloral / Cat Grant (voice) | Floral / Cat Grant (voice) |
