Several important historical events occurred on the planes with call sign Air Force One. These events are described within the backdrop of the evolution of the presidents' airplanes.
| Actor | Role |
|---|---|
 Charlton HestonHost and Narrator | Host and Narrator |
 John F. KennedySelf (archive footage) | Self (archive footage) |
 Franklin D. RooseveltSelf (archive footage) | Self (archive footage) |
 Lyndon B. JohnsonSelf (archive footage) | Self (archive footage) |
 Harry S. TrumanSelf (archive footage) | Self (archive footage) |
 Jimmy CarterSelf | Self |
 George H. W. BushSelf | Self |
 Gerald FordSelf | Self |
 Henry KissingerSelf | Self |
 Dwight D. EisenhowerSelf (archive footage) | Self (archive footage) |
 Richard NixonSelf (archive footage) | Self (archive footage) |
 Ronald ReaganSelf | Self |