Malcolm and Lily try to start their lives as they watch Malcolm's grandparents' fall apart.
| Actor | Role |
|---|---|
| JJonathan RosenMalcolm | Malcolm |
 Lola KirkeLily | Lily |
 Dominic ChianeseBart | Bart |
 Joanna MerlinMiriam | Miriam |
 Rosie PerezZoe | Zoe |
 Ellen BarkinLucy | Lucy |
 Scott CohenMick | Mick |
 Merwin GoldsmithHirsch | Hirsch |
 Sondra JamesRose | Rose |
| AAudrey TurnerKatrina | Katrina |
| MMichaela AntonellaTeenage Girl | Teenage Girl |
 Mike FaistTeenage Boy | Teenage Boy |
 Gurdeep SinghJuice Artisans Manager | Juice Artisans Manager |
 Alison WrightTherapist | Therapist |
| HHarold HoffmanMelvin | Melvin |
| CCassandra JenkinsParty Musician | Party Musician |