 David SuchetDr. Benjamin Cisco | Dr. Benjamin Cisco |
 Max BrownRichard Short | Richard Short |
 Jenny AgutterCatherine Cisco | Catherine Cisco |
 Adrian DunbarFrank O'Connor | Frank O'Connor |
 Nadia Cameron-BlakeyDI Anna Freedland | DI Anna Freedland |
 Charity WakefieldLaura O'Connor | Laura O'Connor |
 Gugu Mbatha-RawRose | Rose |
 Richard RiddellBill | Bill |
| AAdam HowesStephen O'Connor | Stephen O'Connor |
| RRebecca HobbsLawson/Ms Draper | Lawson/Ms Draper |
 Sara StewartAlison Barber | Alison Barber |
 Ricky NixonPC Stanley | PC Stanley |
| SSimeon MoorePC Sawyer | PC Sawyer |
| LLeandra AshtonWaitress | Waitress |
 Bill FellowsMurphy | Murphy |
 Vivienne GibbsStaff Nurse | Staff Nurse |
 Layla AmirCustomer (Uncredited) | Customer (Uncredited) |
| SSimon ColemanForensic Examiner (Uncredited) | Forensic Examiner (Uncredited) |
 Amita DhiriMansfield (Uncredited) | Mansfield (Uncredited) |
 Ece DizdarWaitress (Uncredited) | Waitress (Uncredited) |
 Mike FachertyDiner (Uncredited) | Diner (Uncredited) |
 Daniel HillMr. Jones (Uncredited) | Mr. Jones (Uncredited) |
| HHilary HodsmanMother (Uncredited) | Mother (Uncredited) |
| MMichelle MacErleanWPC Webb (Uncredited) | WPC Webb (Uncredited) |
 Freya ParkerScene of Crime Officer (Uncredited) | Scene of Crime Officer (Uncredited) |
 Philip PritchardForensic Officer (Uncredited) | Forensic Officer (Uncredited) |
| LLaurence RichardsonPolice Officer (Uncredited) | Police Officer (Uncredited) |
 Girija ShettarJournalist (Uncredited) | Journalist (Uncredited) |
| IIan StaceyPolice Sergeant (Uncredited) | Police Sergeant (Uncredited) |
| AAndrew VenningNeighbour (Uncredited) | Neighbour (Uncredited) |