Santa has an accident at Fred's house on Christmas Eve, Fred and Barney have to continue his run for him.
| Actor | Role |
|---|---|
 Henry CordenFred Flintstone (voice) | Fred Flintstone (voice) |
 Mel BlancBarney Rubble / Dino (voice) | Barney Rubble / Dino (voice) |
 Jean Vander PylWilma Flintstone / Pebbles Flintstone (voice) | Wilma Flintstone / Pebbles Flintstone (voice) |
 Gay AuttersonBetty Rubble (voice) | Betty Rubble (voice) |
 Lucille BlissBamm Bamm Rubble (voice) | Bamm Bamm Rubble (voice) |
 John StephensonMr. George Nate Slate (voice) | Mr. George Nate Slate (voice) |
 Don MessickEd the Foreman / Otis (voice) | Ed the Foreman / Otis (voice) |
 Virginia GreggMrs. Santa Claus (voice) | Mrs. Santa Claus (voice) |
 Hal SmithSanta Claus (voice) | Santa Claus (voice) |