A tale of the World War I love affair, begun in Italy, between American ambulance driver Lt. Frederic Henry and British nurse Catherine Barkley. Eventually separated by Frederic's transfer, tremendous challenges and difficult decisions face each as the war rages on.
| Actor | Role |
|---|---|
 Helen HayesCatherine Barkley | Catherine Barkley |
 Gary CooperLt. Frederic Henry | Lt. Frederic Henry |
 Adolphe MenjouMajor Rinaldi | Major Rinaldi |
 Mary PhilipsHelen Ferguson | Helen Ferguson |
 Jack La RuePriest | Priest |
 Blanche FridericiHead Nurse | Head Nurse |
 Mary ForbesMiss Van Campen | Miss Van Campen |
 Gilbert EmeryBritish Major | British Major |
 Henry ArmettaBonello the Ambulance Driver (uncredited) | Bonello the Ambulance Driver (uncredited) |
 Herman BingSwiss Postal Clerk (uncredited) | Swiss Postal Clerk (uncredited) |
| AAgostino BorgatoHospital Porter Giulio (uncredited) | Hospital Porter Giulio (uncredited) |
 Marcelle CordaySwiss Nurse (uncredited) | Swiss Nurse (uncredited) |
 Gino CorradoItalian Soldier (uncredited) | Italian Soldier (uncredited) |
 William IrvingFrustrated Opera Singing Friend (uncredited) | Frustrated Opera Singing Friend (uncredited) |
 Doris LloydNurse (uncredited) | Nurse (uncredited) |