Sis is the maid in the Higgins home, adjoining that of Prof. Doolittle, a physical culture specialist. Sis takes up the study of "fysical culture" with disastrous results, for her throwing out of the medicine ball renders the Doolittle maid a subject for hospital treatment. Sis is then loaned to the Professor's establishment.
| Actor | Role |
|---|---|
| RRose MelvilleSis Hopkins | Sis Hopkins |
| HHenry MurdockProfessor Doolittle | Professor Doolittle |
| OOlive WestThe Professor's Sister | The Professor's Sister |
| CC.D. PeruchiSkull N. Bones | Skull N. Bones |
| RRichard PurdonMr. Higgins | Mr. Higgins |
| FFrances Ne MoyerThe Maid | The Maid |