 Dave FoleyFlik (voice) | Flik (voice) |
 Kevin SpaceyHopper (voice) | Hopper (voice) |
 Julia Louis-DreyfusAtta (voice) | Atta (voice) |
 Hayden PanettiereDot (voice) | Dot (voice) |
 Phyllis DillerQueen (voice) | Queen (voice) |
 Richard KindMolt (voice) | Molt (voice) |
 David Hyde PierceSlim (voice) | Slim (voice) |
 Joe RanftHeimlich / Additional Voices (voice) | Heimlich / Additional Voices (voice) |
 Denis LearyFrancis (voice) | Francis (voice) |
 Jonathan HarrisManny (voice) | Manny (voice) |
 Madeline KahnGypsy Moth (voice) | Gypsy Moth (voice) |
 Bonnie HuntRosie (voice) | Rosie (voice) |
 Michael McShaneTuck / Roll (voice) | Tuck / Roll (voice) |
 John RatzenbergerP.T. Flea (voice) | P.T. Flea (voice) |
 Brad GarrettDim (voice) | Dim (voice) |
 Roddy McDowallMr. Soil (voice) | Mr. Soil (voice) |
 Edie McClurgDr. Flora (voice) | Dr. Flora (voice) |
 Alex RoccoThorny (voice) | Thorny (voice) |
| DDavid OssmanCornelius (voice) | Cornelius (voice) |
 Carlos AlazraquiAdditional Voices (voice) | Additional Voices (voice) |
 Jack AngelAdditional Voices (voice) | Additional Voices (voice) |
 Bob BergenAdditional Voices (voice) | Additional Voices (voice) |
 Kimberly J. BrownAdditional Voices (voice) | Additional Voices (voice) |
 Rodger BumpassAdditional Voices (voice) | Additional Voices (voice) |
 Anthony BurchAdditional Voices (voice) | Additional Voices (voice) |
 Jennifer DarlingAdditional Voices (voice) | Additional Voices (voice) |
| RRachel DaveyAdditional Voices (voice) | Additional Voices (voice) |
 Debi DerryberryAdditional Voices (voice) | Additional Voices (voice) |
 Paul EidingAdditional Voices (voice) | Additional Voices (voice) |
 Jessica EvansAdditional Voices (voice) | Additional Voices (voice) |
