 James FrancoAron Ralston | Aron Ralston |
 Kate MaraKristi Moore | Kristi Moore |
 Amber TamblynMegan McBride | Megan McBride |
 Clémence PoésyRana | Rana |
 Lizzy CaplanSonja Ralston | Sonja Ralston |
 Kate BurtonAron's Mom | Aron's Mom |
 Treat WilliamsAron's Dad | Aron's Dad |
 Sean BottAron's Friend | Aron's Friend |
 Fenton QuinnBlue John | Blue John |
| JJohn LawrenceBrion | Brion |
 Pieter Jan BruggeEric Meijer | Eric Meijer |
| RRebecca C. OlsonMonique Meijer | Monique Meijer |
| JJeffrey WoodAndy Meijer | Andy Meijer |
 Norman LehnertDan | Dan |
 Darin SouthamZach | Zach |
| KKoleman StingerAron Age 5 | Aron Age 5 |
 Bailee Michelle JohnsonSonja Age 10 | Sonja Age 10 |
| PParker HadleyAron Age 15 | Aron Age 15 |
| PPeter Joshua HullBoy on Sofa | Boy on Sofa |
| TTerry S. MercerHelicopter Pilot | Helicopter Pilot |
| XXmas LutuHelicopter Co-Pilot | Helicopter Co-Pilot |
| LLuke DrakeAron's Friend (uncredited) | Aron's Friend (uncredited) |
| RRobert BearAron's Friend (uncredited) | Aron's Friend (uncredited) |
 Brad JohnsonAron's Friend (uncredited) | Aron's Friend (uncredited) |
 Stacey Ann TurnerAron's Friend (uncredited) | Aron's Friend (uncredited) |
| ZZachary HaycockReporter (uncredited) | Reporter (uncredited) |
 Lonzo LigginsReporter (uncredited) | Reporter (uncredited) |
| SSamantha MarsdenMedia Person / Basketball Game Fan (uncredited) | Media Person / Basketball Game Fan (uncredited) |
| JJohnny AhnBasketball Fan (uncredited) | Basketball Fan (uncredited) |
| CChristopher K. HagadoneBasketball Fan (uncredited) | Basketball Fan (uncredited) |
